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Microbiology Department October 15, 1999
The following page contains data from seven
strains of potentially pathogenic bacteria. They are the same strains that
have been tested in Minimum Inhibitory Concentration tests (MIC) against
American Silver's ASAP solution. This data contains, along with the data
on the ASAP solution, MIC's performed on each bacteria versus
representative of five different classes of antibiotics. These tests were
performed to ascertain the relative antimicrobial activity of the ASAP
solution when compared to other antibiotics. As the data suggests, the
ASAP solution has a greater ability on average to kill the bacteria tested
than four of the five antibiotics to which it was compared. Each
antibiotic has its own niche to fill, but not one of the antibiotics
tested work equally well on every bacterial strain that it was tested
against, the ASAP solution had similar results for each bacteria - it was
able to kill each bacteria tested. Furthermore, there are
antibiotic-resistant strains that may or may not succumb to a given
antibiotic. This is where the ASAP solution data comes in-although the
ASAP solution may not have inhibited a strain of bacteria at a lower
concentration than a given antibiotic, it inhibited every strain of
bacteria tested, which is more than can be suggested for some of the other
antibiotics, given the data. Minimum Inhibitory Concentration of Antibiotics from Five Different Classes versus ASAP Solution performed by D. Revelli, Brigham Young University
The average was taken from all data points to
obtain the average minimum inhibitory concentration for an antibiotic.
Then a standard deviation was determined to give an error. All
concentrations were calculated in parts per million (ug/ml). The
abbreviation "no inh," stands for "No inhibition of growth." And ">"
means that the measurement of the bacteriocidal concentration was beyond
the limits of the test. Information is listed as "MIC (level at which
bacteria was inhibited)/MBC (level at which bacteria were killed)/number
of tests performed."
David A. Revelli Microbiologist Brigham Young
University Dr. Ron W. Leavitt,
Ph.D. Professor of Microbiology/Molecular
Biology Brigham Young University |
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